European Psychiatry - Volume 33 - March 2016

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24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805 S547
EV617
Insight and aggressive behavior in
acute schizophrenic patients
S. Campi ∗, C. Esposito , P. Andreassi , P. Bandinelli ,
P. Girardi , G. Ducci , C. Cannizzaro , C. Cacciari , G. Spalletta
1 Rome, Italy
2 IRCCS Santa Lucia Fondation, Neuroscience, Rome, Italy
3 SPDC San filippo Neri ASL RmE, Mental Health Department, Rome,
Italy
4 Sant’Andrea hospital Sapienza University, Mental Health, Rome,
Italy
5 SPDC San Filippo Neri ASL RmE, Mental Health, Rome, Italy
6 IRCCS Santa Lucia foundation, Neuroscience, Rome, Italy
∗ Corresponding author.
Introduction Aggressive behavior in wards is associated to poor
treatment compliance and low clinical insight. Most studies
focused on the clinical and cognitive dimensions of insight, while
the relationship between metacognitive dimension and aggres-
sive behaviors was not investigated. Our aim was to understand
what relationship occurs between dimensions of insight (metacog-
nitive, cognitive, clinical), and specific aggressive behaviors in acute
patients.
Methods We recruited 75 acute schizophrenic patients using:
AQ; MOAS; IS; PANSS; BCIS.
Results A positive correlation between the IS score and the hos-
tility, angry and physical aggression sub-scores of the AQ was
highlighted, while no correlation between the score of IS andMOAS
total score was found. No correlation between the score of the
PANSS G12 item and the AQ scores and MOAS was found, and no
correlation between BCIS scores, MOAS and AQ scores was found.
Conclusions In our patients, a higher level of metacognitive
insight, but not clinical nor cognitive insight, was associated to
higher levels of hostility. We suggest that a higher ability to moni-
tor and appraise one’s own altered processes of thought and related
discomfort, feeling of destabilization and loss of control, could con-
tribute to enhance resentment and suspiciousness. Findings help
develop specific therapeutic strategies to enhance metacognitive
and self-monitoring abilities, helping patient’s understanding of
the illness, improving compliance with treatment, and patient’s
quality of life. Our results support the multidimensional nature
of insight in schizophrenia, confirming that clinical, cognitive and
metacognitive dimensions are independent though related facets
of the phenomenon of insight in schizophrenia.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV618
Loxapine for agitation in psychiatric
patients who consult in emergency
medical services
M.Á. Carrillo ∗, M.J. Martínez , P. Botías , I. Imbernón ,
M. Martínez-Carlón , M. Fueyo , C. Calero , N. Megias , S. Pina ,
M. Gavilan , M.P. Sanchez , J. Sanchez , P. Chacon
University Hospital of Murcia Virgen Arrixaca, Psychiatry, Murcia,
Spain
∗ Corresponding author.
Introduction The DSM-5 defines psychomotor agitation as exces-
sive motor activity associated with a feeling of inner tension. The
activity is usually nonproductive and repetitious and consists of
behaviors such as pacing, fidgeting, wringing of the hands, pulling
of clothes, and inability to sit still. This kind of behavoir occurs in up
to 25% of psychiatrics patients who consult in emergency medical
services.
Objective The main objective was to determine the efficacy of
loxapine inhalation powder in acute agitation.
Methods Ten agitated psychiatric patients scored Positive and
Negative Syndrome Scale – Excited Component (PANSS-EC) base-
line and ten minutes after the administration of ADASUVE® .
Results The efficacy of loxapine 10mg in the acute treatment of
agitation was established in a short-term (10minutes).
Conclusions Loxapine is the first and only orally inhaled med-
ication for the acute treatment of agitation associated with
psychiatrics disorders, which is a tool easy-to-use in emergency
medical services.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV619
Change of mood in relation with the
seasons
R. de la Mata Hidalgo ∗, M. de la Mata Hidalgo ,
I. Valriberas Herrera , O.E. Ana , L. Al Chaal Marcos ,
C. González Soria , L. Sánchez Pernas , C. Exposito Montes
1 Instituto de Investigación Biomédica de Salamanca, Psychiatry,
Salamanca, Spain
2 Facultad Medicina Córdoba, Psychiatry, Córdoba, Spain
∗ Corresponding author.
Introduction Emergency situations related to mental disorders
represent a significant proportion of all medical emergencies. Over
the last years we have been witness to an upturn in the incidence
of psychiatry emergency service because to change of mood.
Objective To determine the profile of the patient who requires
psychiatric attentionwith changing of mood in our area in different
seasons.
Methodology This is a prevalence and prospective study in which
the dependent variable is taken as change of mood and we also use
three more independent variables that are age sex and seasonality.
The seasonality (spring period and summer period) will be at the
same time the form of divided the population in two groups to
compare.
Results Out of all the consultations for changing of mood in the
emergency service during the first period (113 patients), 34% were
men and 66% were women. The age range of 36–50 years was more
frequent for women and the age range of 51–65 years was more
frequent for men. In the second period (with 162 patients), 137
women (86%) and 25 men (14%). In this case, the most common
age range was 36–50 years, both for women and for men.
Conclusions The epidemiological and clinical characteristics of
patients with changing of mood assessed by the emergency service
are described from a naturalistic approach.
Which Chi2 we will discover if the population who has been taken
between woman and man is significant and with the median, we
will also determine if the age ranges are enough significant to con-
firm our hypothesis.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV620
Atypical psychosis in emergency: A
case review
A. Espinosa Benavides ∗ anahuja Mu˜noz
1 Instituto Psiquiátrico José Germain, Psiquiatría, Leganés, Spain
2 Hospital Universitario de Fuenlabrada, Psiquiatría, Fuenlabrada,
Spain
∗ Corresponding author.
The authors describe the presentation of a case of atypical psy-
chosis in the emergency services, and describe the unusual clinical
features of manifestation of psychotic disorders.