European Psychiatry - Volume 33 - March 2016

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S168 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S116–S348
3 University of Limerick, Graduate Entry Medical School, Limerick,
Ireland
∗ Corresponding author.
Introduction Traditionally psychomotor subtypes have been
investigated in patients with delirium in different settings and it
has been found that those with hypoactive type is the largest pro-
portion, often missed and with the worst outcomes.
Aims and objectives We examined the psychomotor subtypes in
an older age inpatients population, the effects that observed clinical
variables have on psychomotor subtypes and their associationwith
one year mortality.
Methods Prospective study. Participants were assessed using the
scales CAM, APACHE II, MoCA, Barthel Index and DRS-R98. Pre-
existing dementia was diagnosed according to DSM-IV criteria.
Psychomotor subtypeswere evaluatedusing the two relevant items
of DRS-R98. Mortality rates were investigated one year after admis-
sion day.
Results The sample consisted of 200 participants [mean age
81.1 ± 6.5; 50% female; pre-existing cognitive impairment in 126
(63%)]. Thirty-four (17%) were identified with delirium (CAM+).
Motor subtypes of the entire sample was: none: 119 (59.5%), hypo:
37 (18.5%), mixed: 15 (7.5%) and hyper: 29 (14.5%). Hypoactive
and mixed subtype were significantly more frequent to delirious
patients than to those without delirium, and none subtype more
often to those without delirium. There was no difference in the
hyperactive subtype between those with and without delirium.
Hypoactive subtype was significant associated with delirium and
lower scores in MoCA (cognition), while mixed was associated
mainly with delirium. Predictors for one-year mortality were lower
MoCA scores and severity of illness.
Conclusions Psychomotor disturbances are not unique to delir-
ium. Hypoactivity, this “silent epidemic” is also part of a
deteriorated cognition.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW153
Use of antipsychotics and
antidepressants in patients with HIV
P. Mu˜noz-Calero ∗, F. García Sánchez , N. Rodriguez Criado ,
R. Martín Aragón , J.F. Cruz Fourcade , S. Bravo Herrero ,
B. Sánchez Sánchez
Hospital Universitario de Móstoles, Psychiatry, Móstoles, Spain
∗ Corresponding author.
Introduction Psychological distress appears in the majority of
people infected with HIV. Depression is the most important affec-
tion, the prevalence in comparison with general population arises
to 37%. Psychotic symptoms in patientswithHIV are a very frequent
entity, in some cases, these symptoms are pre-existent in others the
evolution of the infection or a medical cause related with the infec-
tion can cause its apparition. Psychosis and depression in patients
with HIV have some clinical and therapeutical considerations.
Antidepressants and antipsychotics have many pharmacological
interactions with antiretroviral therapy.
Objectives Review the efficacy and safety of antidepressants and
antipsychotics in patients with HIV infection.
Methods PubMed was searched for articles published between
1966 and January 1, 2015, using the search terms HIV, AIDS, depres-
sion, phycosis, antipsychotics, antidepressants, antiretrovirals. We
selected randomized placebo controlled or active comparator con-
trol trials.
Results Twelve studies for depression treatment and 2 studies
for psychosis treatment in patients with HIV infection. Selective
serotonin reuptake inhibitors (SSRI) especially fluoxetine and tryci-
clic antidepressants are effective in treating depressive symptoms
in patients with HIV infection. Testosterone and stimulants have
been used in patients with mild depressive symptoms, however
studies with these agents had a small sample size. Haloperidol
and chlorpromazine were effective for AIDS delirium, there are not
controlled trials with other antipsychotics.
Conclusions Psychiatrists must be concern about the clinical
particularities of patients with HIV and depression or psychotic
symptoms. The election of antidepressant or antipsychotic has to be
made very carefully because of their side effects and interactions.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW154
Living with Parkinson disease – the
central role of primary care physicians
and a multidisciplinary approach
M. Oliveira ∗, M. Marinho , C. Santos
Centro Hospitalar São João - EPE, Psychiatry and Mental Health
Clinic, Porto, Portugal
∗ Corresponding author.
Introduction Parkinson disease is a frequent neurodegenerative
disorder. Presence of psychopathology is well described in this ill-
ness, nevertheless the etiology is still unknown.
Methods and aims The authors present a clinical case of a patient
with idiopathic Parkinson disease with depressive symptoms after
the decline of his functioning. We aim to emphasize the impor-
tance of amultidisciplinary approach and the central role of general
physicians in screening these situations.
Results The patient is a male with 64 years old, reformed with
a personal history of hypertension. With 62 years old he started
with mild motor complaints that got worse over time, culminat-
ing after a year and half on him being almost dependant for most
of his daily activities. He also started to express feelings of sad-
ness, despair, and recurrent thoughts of death. He refused to seek
out medical help, but was convinced by his wife to consult his
general physician that observed the patient and referenced him
to Neurology and Psychiatry consultations. He also started ser-
traline 50 mg/day. He was diagnosed with Parkinson disease and
started medication with ropinirole, levodopa and carbidopa with
a good response. In Psychiatry consultation the dose of sertraline
was increased to 100mg/day with improvement, and it was pro-
vided information on the disease to the patient and family and also
supportive psychotherapy.
Conclusions General physicians have a privileged position on
screening patients with psychopathology when other physical con-
ditions or illnesses are present. The fast and correct referencing of
these patients can improve the prognosis.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW155
Psychological mechanisms of the
formation of non-psychotic mental
disorders in patients with
hyperthyroidism
O. Pityk ∗ Pityk uzhda
1 Ivano-Frankivsk National Medical University, Department of
Psychiatry- Narcology and Medical Psychology, Ivano-Frankivsk,
Ukraine
2 Ivano-Frankivsk National Medical University, Department of
Neurology, Ivano-Frankivsk, Ukraine
3 Ivano-Frankivsk Regional Children Hospital, Department of
Ophthalmology, Ivano-Frankivsk, Ukraine
∗ Corresponding author.