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Page Background European Psychiatry 33S (2016) S12–S13

Available online at

ScienceDirect

www.sciencedirect.com

24th European Congress of Psychiatry

State-of-the-art

SA01

Psychosocial intervention in

schizophrenia

T. Wykes

Institute of Psychiatry – Psychology and Neuroscience – KCL,

Psychology, London, United Kingdom

Psychological treatments aimed at symptoms or behaviours that

impede recovery now have a relatively strong database but it is not

clear which treatments are more effective and when they should

be applied. For large-scale roll out we need to consider which

are the most helpful and cost-effective at which stage of the ill-

ness and to which individuals. This requires knowledge of how

service users ascribe value to different outcomes and treatments

as well as which individuals are likely to benefit the most from

different treatments to produce a coherent mental health recov-

ery programme. Tailoring treatment requires an understanding

of adherence requirements as well as therapeutic interactions to

explain how therapy fits with the service users’ personal goals. Not

all information for making these clinical decisions is embedded in

any database so the burden on research is to provide enough infor-

mation to signal to health professionals the best course of action.

More research on dissemination of treatment approaches as well

as training and supervision requirements is needed in the form of

dissemination science if patients with a diagnosis of schizophrenia

are to receive the best intervention programme.

Disclosure of interest

The author has not supplied his declaration

of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.803

SA02

Nutrition, sleep, physical exercise:

Impact on mental health

W. Rössler

University of Zurich, Psychiatric University Hospital, Zürich,

Switzerland

Until recently nutrition and various other lifestyle factors were

predominantly in the focus of medical disciplines like cardiology,

endocrinology or gastroenterology. As mental disorders are mul-

tifactorial diseases and as such are complex, emerging evidence

suggests that nutrition, exercise and sleep also play an important

role in the aetiology, progression and treatment of mental disor-

ders. In this regard research has mostly focused on depression and

anxiety, but there is also evidence for other mental disorders like

schizophrenia or autism. Some details concerning the relationship

between diet and sleep on neuro-transmitter processes, immune-

inflammatory pathways or oxidative stress will be demonstrated.

Modifications of life style factors and diet are increasingly

recognized as potential therapeutic options. Mostly used are

nutrient-based supplements and essential elements in combina-

tion. But also healthy diet patterns with a high intake of vegetable,

fruits and fish have proven beneficial in the treatment. If we better

understand the microbiota-gut-brain axis and its impact on behav-

ior, mood and cognitive processes, diet and lifestyle factors can

not only contribute to the treatment but also to the prevention of

mental disorders.

Disclosure of interest

The author has not supplied his declaration

of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.804

Drinking patterns we should accept while

reducing harmful alcohol consumption

SA03

Can alcohol-dependent patients really

reduce their alcohol consumption

over time?

K. Mann

Central Institute of Mental Health, Medical Faculty Mannheim,

University of Heidelberg, Addiction Research, Mannheim, Germany

Introduction

Treatment of alcohol dependent patients is moder-

ately successful but it only reaches about 10% of the population in

need. A new harm reduction strategy aims at abstinence in the long

run but claims to benefit patients already early on by reducing their

alcohol consumption.

Objectives

A brief outline of the debate on abstinence versus con-

trolled drinking will be followed reporting several RCTs striving for

reduced drinking in alcohol dependent patients.

Aims

The participant will find guidancewhether and how to treat

patients following this new approach.

Results

Studies testing behavioural treatments and counselling

(MATCH, UKATT) indicate that a reduction over time is possible.

Using nalmefene (a mu and delta opioid antagonist and a partial

agonist) RCTs withmore than 2500 patients were performed show-

ing a benefit over placebo. On this basis the EMA approved this

drug for the reduction of alcohol consumption in alcohol dependent

0924-9338/$ – see front matter