European Psychiatry - Volume 33

European Psychiatry 33S (2016) S18–S55

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24th European Congress of Psychiatry

Symposium

Addictions and addictive behaviours:

Psychopathological, philosophical and ethical

reflections

S01

The synthetic psychosis substances

induced: A clinical case study

G. DiPetta (Neuropsychiatrist, Addiction Center Consultant)

Department of Mental Health, Naples, Italy

The presentation intends to examine a new kind of clinical psychi-

atric syndrome, called by the author “synthetic psychosis”, which

can occur in people who abuse novel psychoactive substances

(NPS). This syndrome will be considered from both a psychopatho-

logical and a phenomenological perspective. The contemporary

trend of poly-abuse of NPS in young people can lead to a sort of

very intense paraphrenic state characterised by continuous hal-

lucinations and formed by a mental automatism syndrome and

by secondary (interpretative) delusions. The clinical case of G.,

discussed in this paper, is an exemplary case of this synthetic

psychosis. The psychopathological understanding of the core sym-

ptomatology of the patient examined has been fundamental for the

successive therapeutic approach. If this attempt at understanding

is ineffective, the frequent consequences include: the worsening

of the psychopathology and addiction; the patient’s admission into

a psychiatric hospital; his/her arrest for crimes related to antiso-

cial behaviour; a diffusion of infective diseases commonly found

in addicts; more frequent overdoses; aggressive behaviour; an

increase in the costs of public health system and, finally, the suicide

of the patient

[1] .

Disclosure of interest

The author has not supplied his declaration

of competing interest.

Reference

[1] MD, Psychiatrist and Neurologist, S. Maria delle Grazie Hospi-

tal, Female Prison, Addiction Centre Consultant, Mental Health

Department, ASL Naples 2 North, Italy Vice-president of Italian

Society of Phenomenological Psychopathology.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.817

Affective and psychotic psychopathology during

adolescence and early adulthood: the dynamic

developmental interplay between genes,

structures and functions

S02

Corollary discharge, auditory

hallucinations and schizophrenia –

a structural network analysis

R. Henze

1 , 2 ,

∗

, C . G

och

3 , J. R

ichter

1 , 2 , P . P

arzer

2 , R. B

runner

2 ,

F. Resch

2 , B. S

tieltjes

German Cancer Research Center, Department of Radiology,

Heidelberg, Germany

University Hospital of Heidelberg, Department of Child and

Adolescent Psychiatry, Heidelberg, Germany

German Cancer Research Center, Junior Group Medical Image

Computing, Heidelberg, Germany

University of Basel, Clinic for Radiology and Nuclear Medicine,

Basel, Switzerland

∗

Corresponding author.

Introduction

Corollary discharges (CDs) are the reason most

people cannot tickle themselves. They are the brain’s way of distin-

guishing whether a stimulus is associated with one’s own actions

or something else. In neural terms, CDs are copies of motor plans

that are propagated to sensory cortex where they can be compared

with inputs. A range of phenomena associated with schizophre-

nia from auditory hallucinations to visual processing difficulties

to the ability of patients to tickle themselves can be explained as

pathologies in CD mechanisms. Auditory hallucinations for exam-

ple involve patients failing to perceive themselves as the author of

their own inner speech.

Objectives and aims

To test whether schizophrenia is associated

with a structural network disruption that could impair CD signals

involved in language processing, adolescents with schizophrenia

were examined using magnetic resonance imaging and compared

to healthy controls.

0924-9338/$ – see front matter