Table of Contents Table of Contents
Previous Page  802 / 812 Next Page
Information
Show Menu
Previous Page 802 / 812 Next Page
Page Background

S798

24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805

EV1412

Post-thalamic stroke apathy, a review

and case report

C. Nu˜nez Sande

1 ,

, T.M. Torres Rincon

2

, J.L. Fernández Hierro

3

1

Servicio de Psiquiatría XXIV Vigo, Servicio de Psiquiatría XXIV Vigo,

Vigo, Spain

2

Servicio de psiquiatría XXIV Vigo, Servicio de psiquiatría XXIV, Vigo,

Spain

3

Servicio de Psiquiatría XXIV Vigo, Unidad de Hospitalización

Psiquiátrica, Vigo, Spain

Corresponding author.

Introduction

Apathy is commonly defined as lack of, or

diminished, emotion, interest, concern, interest and motivation

manifesting as poor engagement with others and loss of pleasure

in usual interests. Occurs in various medical condition (stroke, HIV,

dementia and Parkinson disease) and other psychiatric disorders. It

has been relatedwith thalamus stroke, and seen on clinical practice

as a blunted emotional response and indifference.

Objective

We have tried to link cases of apathy associated with

thalamic stroke and systematically review the literature for similar

case reports.

Methods

We have searched MEDLINE, EMBASE, IBIDS, and the

Cochrane Collaboration Database until October 2015. Published

case reports of apathy in persons who had suffered a brain stroke

were selected.

Results

Support the evidence in the literature of the multidimen-

sional nature of apathy and correlate the psychiatric manifestation

with the neurological findings. We find similar case reports that

could support the anatomical subtract of the apathy and it’s also

correlated with the previous data reports.

Conclusions

These findings are discussed and interpreted in the

seeking of regarding the neurobiological substrate of apathy.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2397

EV1413

A case of neurosarcoidosis presenting

with isolated psychotic symptoms

O. Onur

1 ,

, E. Carpar

1

, Y. Altunkaynak

2

1

Istanbul Bakırkoy Research and Training Hospital for Psychiatry

Neurology and Ne, Psychiatry, Istanbul, Turkey

2

Istanbul Bakırkoy Research and Training Hospital for Psychiatry

Neurology and Ne, Neurology, Istanbul, Turkey

Corresponding author.

Neurosarcoidosis (NS) is a neurologic manifestation of sarcoidosis,

a rare multisystemic granulomatous disease. Although psychiatric

symptoms have been reported to occur in 20% of patients with NS,

isolated NS without any signs of systemic disease is a rarity.

Case

A 56-year-old female admitted to psychiatry clinic due to

complaints of forgetfulness, visual and auditory hallucinations,

inability to go outside alone, washing hands in closet cabin, dif-

ficulty finding words for the last one year, progressing in last

four months. Personal and family background was unremarkable.

Vital signs and physical examination revealed no abnormalities. In

neuropsychiatric examination, Glasgow Coma Scale score was 15

without any meningeal irritation signs or gait abnormalities. Cra-

nial nerves, extrapyramidal, motor, cerebellar, and sensory systems

were intact. All aspects of orientation (time, place and person) were

impaired. She scored12 points out of 30 inMiniMental Test. Speech

was non-fluent with looseness of associations. Impaired recall,

abstract thinking, judgment, behaviour planning and attention

were noted. Visiospatial disorientation and contructional dressing

apraxia were revealed. MR Imaging reported a T2-weighted signal

intensity change in nodular fashion suggesting a granulamatous

lesion. Differential diagnoses included granulomatous diseases,

neoplasms, infections and Behcet’s disease. After necessary exclud-

ing evaluations were undergone, a diagnosis of NS was made due

to increased angiotensin converting enzyme levels in cerebrospinal

fluid. The clinical picture responded well to prednisone treatment

and symptoms resolved within one month.

Conclusion

Increased awareness is essential to identify rare gran-

ulamotous diseases as a differential diagnosis in encountering

psychotic symptoms accompanying demantial clinic presentation.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2398

EV1414

Neurocognitive mechanisms behind

mindfulness

J. Perestrelo

, B. Teixeira

Centro Hospitalar de Vila Nova de Gaia/Espinho, Psychiatry, Porto,

Portugal

Corresponding author.

Introduction

Clinical applications of mindfulness have become

widespread since the introduction of the mindfulness-based stress

reduction (MBSR), a treatment program originally developed for

the management of chronic pain. Neuroimaging techniques have

allowed uncovering the neural mechanisms behind Mindfulness

techniques.

Objective

To review some of the psychological and neural mech-

anisms behind mindfulness practice in order to explore the unique

factors that account for its positive impact on emotional regulation

and health.

Aims

Psychological and neural mechanisms behind mindfulness

practice are reviewed.

Methods

A literature review of the theme is surveyed. Several

articles were searched on Medline with the keywords “mindful-

ness”, “meditation”, “neurobiology” and “neurocognitive”.

Results

Mindfulnessmay achieve effective outcomes in the treat-

ment of anxiety, depression, and other psychopathologies through

the contribution of emotional regulation. Cognitive reappraisal has

been suggested as a core cognitive control skill whereby mindful-

ness practice may regulate emotions. It seems that a neural circuit

comprising the prefrontal cortex (PFC), the anterior cingulate cor-

tex (ACC), the amygdala (A), and the insula (I) are involved in the

unique processes of mindful emotion regulation.

Conclusions

Recent models of mindfulness allow for more rig-

orous examination and operationalization of the method to guide

research. Increasingly investigators are focusing on the impact that

mindfulness has on emotional regulation, which accounts for the

effects on mental health.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2016.01.2399

EV1415

Influence of clinical and

organizational changes in the use of

mechanical restraint. Eight-year

retrospective analysis in Mental

Health Hospital Unit of Jerez de

Frontera

J. Pérez Revuelta

1 ,

, Y. Montero Beltran

2

, L. Fernandez Cepillo

1

,

T. Molina Molina

1

, R. Guerrero Vida

1

, J.M. Villagran Moreno

1

1

Hospital del S.A.S. de Jerez, Clinical Management Unit of Mental

Health, Jerez de la Frontera Cádiz, Spain

2

Servicio Andaluz Salud, Macarena Mental Health Unit, Sevilla, Spain

Corresponding author.