European Psychiatry - Volume 33 - March 2016

648 / 812

S644 24th European Congress of Psychiatry / European Psychiatry 33S (2016) S349–S805
schizophrenia spectrum and other psychotic disorders was 29.4%,
13.7% bipolar disorders, 13.7% personality disorders, 11.8% depres-
sive disorders, 9.8% alcohol use disorders, 3.9% schizoaffective
disorders, 3.9% intellectual disabilities, 3.9% adjustment disorders
with depressed mood, 3.9% obsessive-compulsive and related dis-
orders, 2% substance-related and addictive disorders, 2% feeding
and eating disorders and 2% adjustment disorders with mixed
anxiety and depressed mood. The percentage of psychiatric re-
hospitalization in patients with alcohol use disorders was 60%,
57.1% personality disorders, 50% obsessive-compulsive and related
disorders, 50% schizoaffective disorders, 28.6% bipolar disorders,
26.7% schizophrenia spectrum and other psychotic disorders and
0% in the other inpatients. Why the percentage of psychiatric
re-hospitalization is higher in patients diagnosed with personal-
ity disorder and alcohol use disorders? It would be important to
establish an approach through more appropriate units as alcoholic
detoxification unit and personality disorders unit.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV923
Sub-types of childhood trauma
predicts depressive and anxiety
symptoms in the general population
N. Maric ∗, S. Andric , M. Mihaljevic , T. Mirjanic , Z. Pavlovic
1 Clinical centre of Serbia, school of medicine, university of Belgrade,
Belgrade, Serbia
2 Clinical centre of Serbia, clinic for psyhiatry, Belgrade, Serbia
3 Specialized psychiatric hospital, Kovin, Serbia
∗ Corresponding author.
Background Ubiquitous negative emotional states such as
depression, anxiety and stress in adulthood are related to individual
life scenario, particularly influenced by exposure to environmental
risk factors. Here, we investigated if sub-threshold negative emo-
tional states in general population can be predicted by experience
of trauma in the childhood.
Method A sample of 106 healthy young adult participants from
Belgrade and surroundings (43.4% male, age 29.2 ±6.6 years, mean
IQ 106.4 ±15.9) fulfilled Childhood Trauma Questionnaire (CTQ)
to identify emotional or physical abuse/neglect or sexual abuse.
Present level of negative affectivity was measured by Depression
Anxiety Stress Scale (DASS). Hierarchical linear regression analysis
was conducted to identify subtypes of trauma as predictors of the
negative affectivity.
Results Mean CTQ and DASS scores were 31.2 ±6.7 and
16.4 ± 16.8, respectively. An exposure to given risk factors in the
past correlated significantly with intensity of the present negative
affective states (r = 0.290, P= 0.004). For the prediction of anxiety,
the most important traumatism subtypes were emotional abuse,
emotional neglect and physical abuse (P= 0.001; 0.028; and 0.041,
respectively). Depressive symptoms were predicted only by the
emotional abuse in the past (P = 0.008).
Conclusion Based on clinical samples, findings from the literature
yielded greater risk for mood and anxiety disorders after exposure
to emotional, in comparison to the physical trauma. We confirmed
the same pattern of correlations in the healthy subject’s sample,
who had no history mental disorders. Evaluation of the interac-
tion effects among emotional trauma and genotype is strongly
recommended in the identification of subjects at risk and for the
prevention.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV924
Clinical-psychopathological
peculiarities of the prodromal stage of
psychosis
N.O. Maruta ∗, O.Y. Kutikov , V.S. Bilous , K.Y. Zakal ,
S.O. Yaroslavtsev
Institute of neurology, psychiatry and narcology, NAMS of Ukraine,
department of neuroses and borderline conditions, Kharkov, Ukraine
∗ Corresponding author.
Introduction Under conditions of growing of mental pathology in
population, the European Psychiatric Association proposes an early
detection of such pathology and timelymedical interventions as the
main strategy. First of all, this concerns psychoses at whole, and
schizophrenia particularly, as the most disabling mental disorders.
Here, a special role belongs to early interventions in the prodromal
stage of psychosis (PSP). Such interventions might prevent devel-
opment of the pathological process, promote solving of everyday
and financial problems of patients, an early restoring of cognitive
deficits and social functioning.
Aim To investigate clinical-psychopathological peculiarities and
quality of life (QoL) of patients with PSP 72 patients (first hospi-
talization) with acute polymorph psychotic disorder (F23.0, F23.1)
were examined both in the format of real time and retrospectively.
Methods A clinical-psychopathological and psychometric
(PANSS, Scale of Suicidal Risk, SOPS, Scale for Detection of Clinical-
Dynamic Variant of Course of Prodromal Period, PAS-SI) methods;
the Method for Assessment of Integrative QoL Index.
Results In the patients clinical-psychopathological impairments
in the PSP periodmanifested in form of a lowered stress tolerability
(80.5%), agitation (40.2%), anxious conditions (72.2%), tension, con-
centration and attention problems (68.0%), sleep disorders (93.0%),
contents of thoughts (56.9%). The patients had low QoL indexes on
scales of personality realization (81.9%), psychological well-being
(87.5%), and a general QoL impression (95.8%).
Conclusions The abovementioned clinical manifestations should
be considered as PSP diagnostic criteria, which open possibilities
for an early interventions and prevention of consequences of this
pathology.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV925
Low intensity microwave frequency
electromagnetic fields (EMFs) produce
extensive brain damage and
widespread neuropsychiatric effects
M. Pall
Portland, USA
Low intensity microwave/lower frequency EMFs have been
shown to act via activation of voltage-gated calcium chan-
nels (VGCCs). Pathophysiological effects of such exposures are
produced through excessive Ca2+ signaling and elevated perox-
ynitrite. VGCCs are found at very high densities in neurons and
such EMFs produce diverse effects in animal brains. Elevated
VGCC activity increases susceptibility to various neuropsychi-
atric effects in humans. Fourteen different neuropsychiatric
effects in humans, considered established, have been repeatedly
reported to occur following exposures to microwave frequency
EMFs:Sleep disturbance/insomnia, headache, fatigue/tiredness,
depression/depressive symptoms, dysesthesia, concentra-
tion/attention/cognitive dysfunction, dizziness/vertigo, memory
changes, restlessness/tension/anxiety/stress/agitation/feeling